A computational algebra approach to the reverse engineering of gene regulatory networks
نویسندگان
چکیده
منابع مشابه
A computational algebra approach to the reverse engineering of gene regulatory networks.
This paper proposes a new method to reverse engineer gene regulatory networks from experimental data. The modeling framework used is time-discrete deterministic dynamical systems, with a finite set of states for each of the variables. The simplest examples of such models are Boolean networks, in which variables have only two possible states. The use of a larger number of possible states allows ...
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Reverse engineering of gene regulatory networks has been an intensively studied topic in bioinformatics since it constitutes an intermediate step from explorative to causative gene expression analysis. Many methods have been proposed through recent years leading to a wide range of mathematical approaches. In practice, different mathematical approaches will generate different resulting network s...
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M. Pica Ciamarra, G. Miele, L. Milano, M. Nicodemi, G. Raiconi Università “Federico II”, Dipartimento di Scienze Fisiche, Napoli, Italy & INFN Sezione di Napoli Instituto de F́ısica Corpuscular (CSIC-Universitat de València), Ed. Institutos de Investigación, Apdo. 22085, E-46071 València, Spain. 3 Department of Physics and Complexity Science, University of Warwick, UK. 4 Universitá di Salerno, D...
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ژورنال
عنوان ژورنال: Journal of Theoretical Biology
سال: 2004
ISSN: 0022-5193
DOI: 10.1016/j.jtbi.2004.04.037